Evolving protein interaction networks through gene duplication

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چکیده

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Evolving protein interaction networks through gene duplication.

The topology of the proteome map revealed by recent large-scale hybridization methods has shown that the distribution of protein-protein interactions is highly heterogeneous, with many proteins having few edges while a few of them are heavily connected. This particular topology is shared by other cellular networks, such as metabolic pathways, and it has been suggested to be responsible for the ...

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ژورنال

عنوان ژورنال: Journal of Theoretical Biology

سال: 2003

ISSN: 0022-5193

DOI: 10.1016/s0022-5193(03)00028-6